Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.42 |
| ▸ | TPH1 | P17752 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583819 | 0.79 | AKR1C3 (0.47) | MAPTMEN1KMT2AFAAHPTGS1 | |
| SCHEMBL6585213 | 0.73 | NPY5R (0.55) | MAPTGAACXCR1CXCR2FAAH | |
| SCHEMBL6583477 | 0.69 | EPHX1 (0.45) | EPHX1CXCR1CXCR2TPH1FAAH | |
| SCHEMBL4711533 | 0.69 | KDM4E (0.57) | MAPTMEN1GAAKMT2ALMNA | |
| SCHEMBL23318187 | 0.67 | MAPT (0.53) | MAPTMEN1GAAKMT2ALMNA | |
| SCHEMBL13545406 | 0.64 | MAPT (0.49) | MAPTMEN1GAAKMT2ALMNA | |
| SCHEMBL1883571 | 0.64 | EPHX1 (1.00) | EPHX1MAPTGAACXCR1CXCR2 | |
| SCHEMBL260688 | 0.64 | EPHX1 (1.00) | EPHX1MAPTGAACXCR1CXCR2 | |
| SCHEMBL3152241 | 0.64 | EPHX1 (1.00) | EPHX1MAPTGAACXCR1CXCR2 | |
| SCHEMBL8299088 | 0.64 | ALPL (0.55) | MAPTMEN1GAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | claimed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |