Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583886 | 1.00 | NFE2L2 (0.58) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL6907589 | 0.85 | NFKB1 (0.50) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL3581316 | 0.83 | NFE2L2 (0.62) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL3581314 | 0.83 | NFE2L2 (0.62) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL7941908 | 0.83 | ALDH1A1 (0.50) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL7941901 | 0.83 | ALDH1A1 (0.50) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL29365442 | 0.82 | CA1 (0.62) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL79638 | 0.82 | CA1 (0.62) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL27829211 | 0.82 | NFE2L2 (0.60) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 | |
| SCHEMBL79637 | 0.82 | CA1 (0.62) | NFE2L2MAOBCYP1B1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118144-A | Ursolic acid derivative, preparation method thereof and application thereof in glioma resistance | 中国医学科学院药物研究所 | 2025-06-10 | — | — | CN | disclosed |
| CN-120004889-A | ALK5 kinase inhibitor and preparation method and application thereof | 延边大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-114230519-B | Pleuromutilin cinnamate compounds with drug-resistant bacteria resisting activity, and synthetic method and application thereof | 西咸新区沣厚原创医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114230519-A | Pleuromutilin cinnamate compounds with drug-resistant bacterium resisting activity and synthesis method and application thereof | 陕西科技大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-110776410-B | Triketone compound containing cinnamoyl, preparation method and application thereof | 东北农业大学 | 2020-08-21 | — | — | CN | disclosed |
| WO-2020108481-A1 | THIAMINE COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 上海日馨生物科技有限公司 | 2020-06-04 | — | — | WO | disclosed |
| CN-110776410-A | Triketone compound containing cinnamoyl, preparation method and application thereof | 东北农业大学 | 2020-02-11 | — | — | CN | disclosed |
| US-9540338-B2 | Substituted cinnamic acid amides for treating pain | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-20150322024-A1 | Cinnamic Acid Amide Derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-2940003-A1 | CINNAMIC ACID AMIDE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-6174649-B1 | THERMOSTABILITY AND PHOTOELECTRIC CHARACTERISTICS | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 2001-01-16 | — | — | US | disclosed |
| CN-1051380-C | Thermostable photopolymeric material for liquid crystal alignment | LG PHILIP CO LTD (KR) | 2000-04-12 | — | — | CN | disclosed |
| US-5998101-A | Cinnamate-containing photopolymer for orientation film of liquid crystal display (LCD) and method of forming the orientation film using the photopolymer | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 1999-12-07 | — | — | US | disclosed |
| EP-0937722-A1 | Benzimidazole derivatives as cyclooxygenase-2 inhibitors | PFIZER INC. (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5538823-A | Liquid crystal device utilizing thermostable polymeric material | GOLDSTAR CO., LTD. (KR) | 1996-07-23 | — | — | US | disclosed |
| US-5075488-A | Fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0128006-B1 | A SOIL-DISEASE-CONTROLLING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4709052-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322024-A1 | Cinnamic Acid Amide Derivative | OPRL1, TRPV1, TRPA1 | NFE2L2 648/4885MAOB 3567/4885CYP1B1 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.