SCHEMBL6584544

SCHEMBL6584544

O=C(c1ccccc1)c1ccc(Cl)c(F)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 1/20 0.57
ATM Q13315 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
SRD5A2 P31213 2/20 0.55
ALDH1A1 P00352 1/20 0.52
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
ALOX15 P16050 2/20 0.50
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PBRM1 Q86U86 1/20 0.47
ABCC9 O60706 1/20 0.47
ABCC8 Q09428 1/20 0.47
KCNJ11 Q14654 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27654072 0.98 VCAM1 (0.55) VCAM1ATMTDP1L3MBTL1SRD5A2
SCHEMBL27561994 0.90 SRD5A2 (0.53) VCAM1SRD5A2TSHRHSD17B1HSD17B2
SCHEMBL20555530 0.86 SRD5A2 (0.62) VCAM1ATMTDP1L3MBTL1SRD5A2
SCHEMBL1653008 0.85 NPC1 (0.57) VCAM1ATMTDP1L3MBTL1SRD5A2
SCHEMBL333237 0.82 SRD5A2 (0.78) VCAM1ATMTDP1L3MBTL1SRD5A2
SCHEMBL332679 0.82 ATM (0.61) ATMTDP1L3MBTL1SRD5A2ALDH1A1
SCHEMBL17235790 0.82 ALDH1A1 (0.48) TDP1L3MBTL1ALDH1A1RAB9AALOX15
SCHEMBL479072 0.80 TSHR (0.65) TDP1L3MBTL1SRD5A2ALDH1A1RAB9A
SCHEMBL28736779 0.79 CNR2 (0.59) VCAM1ATMTDP1L3MBTL1SRD5A2
SCHEMBL9428615 0.79 ACHE (0.66) ATMTDP1L3MBTL1SRD5A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114130212-B Method for preparing separation membrane by using small molecular monomers 天津工业大学 2025-02-21 CN claimed
CN-118599118-A Energy-saving and consumption-reducing poly (ether) sulfone and method for synthesizing block copolymer thereof 山东净泽膜科技有限公司 2024-09-06 CN claimed
CN-117384385-A Polysulfone-based block copolymer with nonlinear block structure, and synthetic method and application thereof 天津工业大学 2024-01-12 CN claimed
CN-117264215-A Method for synthesizing polysulfone, polyether sulfone and segmented copolymer thereof by dehydration synchronous polymerization 天津工业大学 2023-12-22 CN claimed
CN-114130212-A Method for preparing separation membrane by using small molecule monomer 天津工业大学 2022-03-04 CN claimed
CN-107805305-B Industrial synthesis method of membrane-grade polyarylethersulfone resin 江门市优巨新材料有限公司 2020-10-27 CN claimed
CN-114130212-B Method for preparing separation membrane by using small molecular monomers 天津工业大学 2025-02-21 CN disclosed
CN-118599118-A Energy-saving and consumption-reducing poly (ether) sulfone and method for synthesizing block copolymer thereof 山东净泽膜科技有限公司 2024-09-06 CN disclosed
CN-117384385-B Polysulfone-based block copolymer with nonlinear block structure, and synthetic method and application thereof 天津工业大学 2024-03-22 CN disclosed
CN-117384385-A Polysulfone-based block copolymer with nonlinear block structure, and synthetic method and application thereof 天津工业大学 2024-01-12 CN disclosed
CN-117301405-A Processing technology of high-transparency resin 镇江利德尔复合材料有限公司 2023-12-29 CN disclosed
CN-117264215-A Method for synthesizing polysulfone, polyether sulfone and segmented copolymer thereof by dehydration synchronous polymerization 天津工业大学 2023-12-22 CN disclosed
CN-116724040-A Nitrogen-containing compounds for organic electroluminescent devices 默克专利有限公司 2023-09-08 CN disclosed
CN-107805305-B Industrial synthesis method of membrane-grade polyarylethersulfone resin 江门市优巨新材料有限公司 2020-10-27 CN disclosed
CN-110903480-A Preparation method of controllable molecular weight polysulfone 万华化学集团股份有限公司 2020-03-24 CN disclosed
CN-106167548-A High-performance poly sulphone resin and synthesis thereof 佛山市珀力玛高新材料有限公司 2016-11-30 CN disclosed
CN-104530418-A Industrial synthesis method of high-thermal-stability terminated polyaryletherketone resin JIANGMEN YOUJU NEW MATERIALS CO LTD 2015-04-22 CN disclosed
CN-104497240-A Industrial synthesis method and application of high-fluidity polyether ether ketone resin JIANGMEN YOUJU NEW MATERIALS CO LTD 2015-04-08 CN disclosed
EP-1448524-A1 PIPERIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY (ESPECIALLY CCR5) AstraZeneca AB (SE) 2004-08-25 EP disclosed
WO-2003042177-A1 PIPERIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY (ESPECIALLY CCR5) ASTRAZENECA AB (SE) 2003-05-22 WO disclosed