Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399614 | 0.90 | SRD5A2 (0.53) | NPC1RAB9ASRD5A2VCAM1HSD17B1 | |
| SCHEMBL7813949 | 0.87 | ACHE (0.49) | NPC1RAB9AL3MBTL1SRD5A2VCAM1 | |
| SCHEMBL1651161 | 0.87 | SRD5A2 (0.52) | NPC1RAB9ASRD5A2ALDH1A1HSD17B1 | |
| SCHEMBL20555530 | 0.86 | SRD5A2 (0.62) | NPC1RAB9AATMTDP1L3MBTL1 | |
| SCHEMBL6584544 | 0.85 | VCAM1 (0.57) | NPC1RAB9AATMTDP1L3MBTL1 | |
| SCHEMBL10398542 | 0.85 | SRD5A2 (0.63) | NPC1RAB9ASRD5A2VCAM1HSD17B1 | |
| Water SCHEMBL27654072 | 0.84 | VCAM1 (0.55) | NPC1RAB9AATMTDP1L3MBTL1 | |
| SCHEMBL333237 | 0.82 | SRD5A2 (0.78) | NPC1RAB9AATMTDP1L3MBTL1 | |
| SCHEMBL332679 | 0.82 | ATM (0.61) | NPC1RAB9AATMTDP1L3MBTL1 | |
| SCHEMBL7813946 | 0.81 | HAO1 (0.46) | NPC1RAB9AL3MBTL1SRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114130212-B | Method for preparing separation membrane by using small molecular monomers | 天津工业大学 | 2025-02-21 | — | — | CN | claimed |
| CN-118599118-A | Energy-saving and consumption-reducing poly (ether) sulfone and method for synthesizing block copolymer thereof | 山东净泽膜科技有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-117384385-A | Polysulfone-based block copolymer with nonlinear block structure, and synthetic method and application thereof | 天津工业大学 | 2024-01-12 | — | — | CN | claimed |
| CN-117264215-A | Method for synthesizing polysulfone, polyether sulfone and segmented copolymer thereof by dehydration synchronous polymerization | 天津工业大学 | 2023-12-22 | — | — | CN | claimed |
| CN-114130212-A | Method for preparing separation membrane by using small molecule monomer | 天津工业大学 | 2022-03-04 | — | — | CN | claimed |
| CN-107805305-B | Industrial synthesis method of membrane-grade polyarylethersulfone resin | 江门市优巨新材料有限公司 | 2020-10-27 | — | — | CN | claimed |
| CN-114130212-B | Method for preparing separation membrane by using small molecular monomers | 天津工业大学 | 2025-02-21 | — | — | CN | disclosed |
| CN-118599118-A | Energy-saving and consumption-reducing poly (ether) sulfone and method for synthesizing block copolymer thereof | 山东净泽膜科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-117384385-B | Polysulfone-based block copolymer with nonlinear block structure, and synthetic method and application thereof | 天津工业大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-117384385-A | Polysulfone-based block copolymer with nonlinear block structure, and synthetic method and application thereof | 天津工业大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-117264215-A | Method for synthesizing polysulfone, polyether sulfone and segmented copolymer thereof by dehydration synchronous polymerization | 天津工业大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-110903480-B | Preparation method of controllable molecular weight polysulfone | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114130212-A | Method for preparing separation membrane by using small molecule monomer | 天津工业大学 | 2022-03-04 | — | — | CN | disclosed |
| US-20080293775-A1 | Substituted Diphenylethers, -Amines, -Sulfides and -Methanes for the Treatment of Respiratory Disease | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | disclosed |
| EP-1963259-A2 | SUBSTITUTED DIPHENYLETHERS, -AMINES, -SULFIDES AND -METHANES FOR THE TREATMENT OF RESPIRATORY DISEASE | AstraZeneca AB (SE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007068894-A2 | SUBSTITUTED DIPHENYLETHERS, -AMINES, -SULFIDES AND -METHANES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |
| EP-0600318-B1 | Asymmetric, halogenated benzophenones and process for their preparation | CLARIANT GMBH (DE) | 1998-04-08 | — | — | EP | disclosed |
| EP-0600318-A1 | Asymmetric, halogenated benzophenones and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293775-A1 | Substituted Diphenylethers, -Amines, -Sulfides and -Methanes for the Treatment of Respiratory Disease | PNMT, SQOR, SMS | NPC1 2239/4885RAB9A 3617/4885ATM 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.