Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465260 | 0.92 | ALDH1A1 (0.39) | ALDH1A1LMNAKEAP1NFE2L2MEN1 | |
| SCHEMBL6581298 | 0.77 | KCNH2 (0.42) | ALDH1A1LMNAKEAP1NFE2L2MEN1 | |
| SCHEMBL6579248 | 0.73 | KCNH2 (0.42) | ALDH1A1LMNAKEAP1NFE2L2MEN1 | |
| SCHEMBL6584556 | 0.71 | KCNH2 (0.41) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL7540170 | 0.71 | KCNH2 (0.40) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL11552606 | 0.69 | MEN1 (0.52) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL7909935 | 0.69 | MEN1 (0.52) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL8933428 | 0.68 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL7143895 | 0.65 | CYP3A4 (0.38) | ALDH1A1LMNAKEAP1NFE2L2MEN1 | |
| SCHEMBL2113301 | 0.63 | RAB9A (0.61) | ALDH1A1MAPTMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214307-A1 | 4-OXYBENZOPYRAN DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021609-A1 | 4-OXYBENZOPYRAN DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |