Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583021 | 0.96 | PPARG (0.51) | PPARGMTNR1AMTNR1BTAAR1TSHR | |
| SCHEMBL6583808 | 0.92 | TAAR1 (0.50) | PPARGMTNR1AMTNR1BTAAR1TSHR | |
| SCHEMBL8896521 | 0.91 | TUBB4A (0.51) | PPARGTSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL8889108 | 0.85 | PPARG (0.46) | PPARGMTNR1AMTNR1BTSHRALDH1A1 | |
| SCHEMBL8175426 | 0.84 | SHBG (0.52) | TAAR1TSHRMAPK1ALOX5LMNA | |
| SCHEMBL6583749 | 0.83 | PPARG (0.47) | PPARGTSHRALOX5CYP3A4TUBB4A | |
| SCHEMBL6584133 | 0.82 | TSHR (0.49) | PPARGTSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL8899122 | 0.81 | PPARG (0.55) | PPARGMTNR1AMTNR1BMAPK1LMNA | |
| SCHEMBL6587646 | 0.81 | PPARG (0.59) | PPARGMTNR1AMTNR1BCYP1A2CYP3A4 | |
| SCHEMBL6583789 | 0.80 | GAA (0.46) | PPARGTSHRALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |