Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583021 | 0.86 | PPARG (0.51) | PPARGALOX5METCYP3A4ALDH1A1 | |
| SCHEMBL6584822 | 0.83 | PPARG (0.49) | PPARGALOX5METCYP3A4TUBB4A | |
| SCHEMBL8896521 | 0.81 | TUBB4A (0.51) | PPARGIGF1RCYP3A4TUBB4ATUBB | |
| SCHEMBL8181764 | 0.79 | CA2 (0.42) | TNKS2CA2AKR1B1CYP3A4ALDH1A1 | |
| SCHEMBL6583573 | 0.79 | PPARG (0.54) | PPARGCA2TP53ALDH1A1TSHR | |
| SCHEMBL6583808 | 0.79 | TAAR1 (0.50) | PPARGALOX5CYP3A4ALDH1A1TSHR | |
| SCHEMBL8889108 | 0.77 | PPARG (0.46) | PPARGCYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL6584133 | 0.76 | TSHR (0.49) | PPARGCA2CYP3A4TUBB4ATUBB | |
| SCHEMBL8340297 | 0.75 | PTPN1 (0.48) | PPARGTNKS2CA2AKR1B1ALOX5 | |
| SCHEMBL7165615 | 0.75 | PPARG (0.41) | PPARGCA2TP53CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |