Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524304 | 1.00 | FPR2 (0.59) | FPR2KMT2AMAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL6582593 | 0.90 | CYP2C19 (0.62) | FPR2KMT2AMAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL6626029 | 0.82 | KMT2A (0.69) | FPR2KMT2AMAPK1ALDH1A1PABPC1 | |
| SCHEMBL6599770 | 0.81 | GAA (0.47) | KMT2ASMN1; SMN2CYP2C19CAPN1ALDH1A1 | |
| SCHEMBL8816132 | 0.81 | FPR2 (0.62) | FPR2KMT2APABPC1MEN1KDM4E | |
| SCHEMBL8816136 | 0.81 | FPR2 (0.62) | FPR2KMT2APABPC1MEN1KDM4E | |
| SCHEMBL6584160 | 0.81 | SMN1; SMN2 (0.57) | MAPK1SMN1; SMN2CYP2C19UBE2N | |
| SCHEMBL10801015 | 0.78 | CTSL (0.54) | ALDH1A1 | |
| SCHEMBL3769914 | 0.77 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1 | |
| SCHEMBL996291 | 0.77 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815080-B1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-06-16 | — | — | EP | disclosed |
| US-6002009-A | Di-substituted 1,4-piperidine esters and amides having 5-HT4 antagonistic activity | BOEHRINGER INGELHEIM ITALIA, S.P.A. (IT) | 1999-12-14 | — | — | US | disclosed |
| WO-1996028424-A1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 1996-09-19 | — | — | WO | disclosed |