Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.33 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588259 | 0.87 | RIOK2 (0.38) | RIOK2PTGDR2BCHEHTR2CADRA1A | |
| SCHEMBL6584761 | 0.81 | RIOK2 (0.38) | RIOK2MAPK10GSK3AMAPK8HIPK1 | |
| SCHEMBL6588483 | 0.80 | NPY5R (0.47) | RIOK2CYP1A2PTGDR2MAPK10GSK3A | |
| SCHEMBL6583451 | 0.80 | MC4R (0.37) | RIOK2PTGDR2MAPK10GSK3AMAPK8 | |
| SCHEMBL6584448 | 0.78 | NPY5R (0.52) | RIOK2CYP1A2PTGDR2MAPK10GSK3A | |
| SCHEMBL6589152 | 0.77 | RIOK2 (0.40) | RIOK2MAPK10GSK3AMAPK8HIPK1 | |
| SCHEMBL6585290 | 0.76 | RIOK2 (0.36) | RIOK2MAPK10GSK3AMAPK8HIPK1 | |
| SCHEMBL6585427 | 0.74 | NPY5R (0.42) | RIOK2CYP1A2MAPK10GSK3AADRA1A | |
| SCHEMBL6585559 | 0.71 | LMNA (0.44) | RIOK2CYP1A2MAPK10GSK3ASLC6A3 | |
| SCHEMBL6582907 | 0.68 | NPY5R (0.67) | RIOK2MAPK10GSK3AMAPK8HIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |