Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587124 | 0.91 | PARP1 (0.43) | PARP1MALT1FLT3 | |
| SCHEMBL6807418 | 0.87 | PARP1 (0.53) | PARP1 | |
| SCHEMBL6587569 | 0.87 | PARP1 (0.39) | PARP1 | |
| SCHEMBL6587344 | 0.79 | PARP1 (0.43) | PARP1DHODHFLT3 | |
| SCHEMBL6802778 | 0.77 | PARP1 (0.61) | PARP1DHODH | |
| SCHEMBL6807422 | 0.77 | MALT1 (0.39) | PARP1MALT1FLT3 | |
| SCHEMBL6585205 | 0.76 | PARP1 (0.42) | PARP1 | |
| SCHEMBL6804441 | 0.73 | PARP1 (0.55) | PARP1 | |
| SCHEMBL6585330 | 0.71 | PARP1 (0.43) | PARP1 | |
| SCHEMBL6589144 | 0.71 | PARP1 (0.42) | PARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |