Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 14/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27075383 | 0.76 | AOC3 (0.52) | LMNAMEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL7033559 | 0.73 | ALOX15 (0.57) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL10353910 | 0.72 | ALOX15 (0.56) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL7242222 | 0.70 | APAF1 (0.64) | ADRA2AADRA2BADRA2CLMNAMEN1 | |
| SCHEMBL1307492 | 0.70 | NISCH (0.54) | ADRA2AADRA2BADRA2CLMNACYP2D6 | |
| SCHEMBL29563733 | 0.70 | MAPT (0.59) | LMNAMEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL1036359 | 0.70 | ADRA2A (0.78) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL11829976 | 0.70 | MAPT (0.59) | LMNAMEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL1741683 | 0.69 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL11859273 | 0.68 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944621-B1 | 2-IMIDAZOLINYLAMINOINDOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | PROCTER & GAMBLE (US) | 2004-09-01 | — | — | EP | disclosed |
| US-6395764-B1 | NOSAL DECONGESTION, RESPIRATORY SYSTEM DISORDERS | THE PROCTER & GAMBLE COMPANY | 2002-05-28 | — | — | US | disclosed |
| US-6162818-A | 2-imidazolinylaminoindole compounds useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 2000-12-19 | — | — | US | disclosed |