Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589130 | 0.86 | CHRM3 (0.58) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL6587443 | 0.80 | OPRL1 (0.43) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL6589592 | 0.77 | ALDH1A1 (0.57) | CHRM3CHRM2CHRM1HTT | |
| SCHEMBL17871674 | 0.74 | ALDH1A1 (0.52) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL6592856 | 0.73 | CHRM2 (0.74) | CHRM3CHRM2CHRM1 | |
| Bromomethane SCHEMBL19839345 | 0.72 | ALDH1A1 (0.50) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL6589288 | 0.72 | GPR119 (0.49) | RBP4 | |
| SCHEMBL6590742 | 0.71 | KEAP1 (0.43) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL4967978 | 0.69 | ALDH1A1 (0.46) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL2596487 | 0.68 | KEAP1 (0.50) | CHRM3CHRM2CHRM1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | claimed |
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |