SCHEMBL6589822

SCHEMBL6589822

Cc1c(-c2cc3cc(OCC(C)c4ccccc4)ccc3o2)oc(=O)c(C)c1O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IGLV6-57 P01721 1/20 0.48
RAB9A P51151 3/20 0.39
MAOB P27338 3/20 0.36
ACHE P22303 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
CA4 P22748 1/20 0.35
CA9 Q16790 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6592532 0.92 IGLV6-57 (0.51) IGLV6-57RAB9AMAOBACHEMEN1
SCHEMBL6591554 0.92 IGLV6-57 (0.39) IGLV6-57RAB9AMAOBACHEMEN1
SCHEMBL27558085 0.87 IGLV6-57 (0.35) IGLV6-57RAB9AMAOBACHEMEN1
SCHEMBL6596608 0.85 ACHE (0.42) RAB9AMAOBACHEMEN1NPC1
SCHEMBL6594463 0.84 RAB9A (0.41) IGLV6-57RAB9AMAOBACHEMEN1
SCHEMBL6591398 0.84 MAOB (0.54) MAOBACHEMEN1NPC1KMT2A
SCHEMBL6594080 0.82 MAPT (0.47)
SCHEMBL6591238 0.82 KMT2A (0.42) RAB9AMAOBMEN1KMT2A
SCHEMBL6593971 0.81 ACHE (0.49) RAB9AMAOBACHEMEN1KMT2A
SCHEMBL6596694 0.80 ACHE (0.48) RAB9AMAOBACHEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1063235-B1 BENZOFURYLPYRONE DERIVATIVES TEIJIN LTD (JP) 2004-05-12 EP disclosed
US-20030186976-A1 Benzofurylpyrone derivatives TEIJIN LIMITED, MICROBIAL CHEMISTRY RESEARCH FOUNDATION 2003-10-02 US disclosed
EP-1063235-A1 BENZOFURYLPYRONE DERIVATIVES TEIJIN LIMITED (JP) 2000-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186976-A1 Benzofurylpyrone derivatives PLIN5, ACSL5, PLIN1 IGLV6-57 4060/4885RAB9A 4399/4885MAOB 3367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.