Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589723 | 0.92 | RXFP1 (0.31) | SLC6A2 | |
| SCHEMBL6589652 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL6593270 | 0.78 | RXFP1 (0.36) | — | |
| SCHEMBL8432079 | 0.78 | RXFP1 (0.36) | — | |
| SCHEMBL6589528 | 0.72 | MMP9 (0.32) | SLC6A2 | |
| SCHEMBL6592827 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL6587765 | 0.65 | LMNA (0.34) | — | |
| SCHEMBL6589626 | 0.64 | RXFP1 (0.50) | SLC6A2 | |
| SCHEMBL8432083 | 0.64 | RXFP1 (0.35) | SLC6A2 | |
| SCHEMBL6593566 | 0.64 | RXFP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703232-B1 | 2,3-Dihydro-1H-isoindole derivates, a process for their preparation and their use as serotonin reuptake inhibitors | AVENTIS PHARMA INC (US) | 2004-06-30 | — | — | EP | claimed |