SCHEMBL659184

SCHEMBL659184

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(Br)c(=O)[nH]c1=O

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.72
TK2 O00142 8/20 0.52
P2RY6 Q15077 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659185 1.00 PYGM (0.72) PYGMTK2P2RY6
SCHEMBL16341964 1.00 PYGM (0.72) PYGMTK2P2RY6
SCHEMBL23804108 0.89 PYGM (0.74) PYGMTK2P2RY6
SCHEMBL16341101 0.88 PYGM (0.68) PYGMTK2
SCHEMBL7182936 0.87 TK2 (0.67) PYGMTK2
SCHEMBL22992480 0.87 TK2 (0.67) PYGMTK2
SCHEMBL20875706 0.87 TK2 (0.67) PYGMTK2
SCHEMBL22992424 0.87 TK2 (0.67) PYGMTK2
SCHEMBL62322 0.87 TK2 (0.67) PYGMTK2
SCHEMBL31685558 0.87 PYGM (0.54) PYGMTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043078-A SIRP-alpha antibodies and conjugates 塔拉克治疗公司 2024-05-14 CN claimed
CN-117836413-A Connexin-4 antibodies and conjugates 塔拉克治疗公司 2024-04-05 CN claimed
EP-4110830-A1 TRANSGLUTAMINASE-MEDIATED CONJUGATION Tallac Therapeutics, Inc. (US) 2023-01-04 EP claimed
CN-115427458-A Transglutaminase mediated conjugation 塔拉克治疗公司 2022-12-02 CN claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
CN-117343990-B Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2025-05-30 CN disclosed
CN-118957041-A Method for determining polymer sequences 牛津纳米孔科技公开有限公司 2024-11-15 CN disclosed
CN-112703256-B Method for determining polymer sequences 牛津纳米孔科技公开有限公司 2024-09-03 CN disclosed
EP-4392076-A1 SIRP-ALPHA ANTIBODIES AND CONJUGATES Tallac Therapeutics, Inc. (US) 2024-07-03 EP disclosed
CN-118043078-A SIRP-alpha antibodies and conjugates 塔拉克治疗公司 2024-05-14 CN disclosed
US-20200032248-A1 METHOD Oxford Nanopore Technologies Inc. (GB) 2020-01-30 US disclosed
US-20190249231-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2019-08-15 US disclosed
EP-3108010-B1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECH LTD (GB) 2018-11-28 EP disclosed
EP-3207152-B1 METHOD OXFORD NANOPORE TECH LTD (GB) 2018-11-28 EP disclosed
US-20170240955-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2017-08-24 US disclosed
US-20170067101-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2017-03-09 US disclosed
US-9410189-B2 Methods of preventing non-specific reactions of nucleotide sequences CO-DIAGNOSTICS, INC. (US) 2016-08-09 US disclosed
US-20120045796-A1 NUCLEIC ACID HOTSTART TECHNOLOGY CO-DIAGNOSTICS, INC. 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM PYGM 1111/4885TK2 114/4885P2RY6 259/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 PYGM 4697/4885TK2 609/4885P2RY6 2900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.