Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.45 |
| ▸ | MAOA | P21397 | 12/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594181 | 0.96 | S1PR1 (0.47) | MAOBMAOAS1PR1S1PR3ACHE | |
| SCHEMBL6597523 | 0.95 | S1PR1 (0.46) | MAOBMAOAS1PR1S1PR3ACHE | |
| SCHEMBL6597903 | 0.92 | MAOB (0.48) | MAOBMAOAACHEALBCYP3A4 | |
| SCHEMBL6593470 | 0.90 | XDH (0.39) | MAOBMAOAS1PR1S1PR3ACHE | |
| SCHEMBL6590213 | 0.88 | MAOB (0.60) | MAOBMAOAS1PR1ACHE | |
| SCHEMBL6595192 | 0.88 | MAOB (0.47) | MAOBMAOAACHEALB | |
| SCHEMBL6593626 | 0.87 | MAOB (0.46) | MAOBMAOAACHEALB | |
| SCHEMBL6593906 | 0.86 | CSF1R (0.45) | MAOBMAOAACHEALBCYP3A4 | |
| SCHEMBL6592300 | 0.85 | PDK2 (0.40) | MAOBMAOAACHEALB | |
| SCHEMBL6594015 | 0.85 | NFE2L2 (0.38) | MAOBMAOAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063235-B1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LTD (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-20030186976-A1 | Benzofurylpyrone derivatives | TEIJIN LIMITED, MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2003-10-02 | — | — | US | disclosed |
| EP-1063235-A1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186976-A1 | Benzofurylpyrone derivatives | PLIN5, ACSL5, PLIN1 | MAOB 3367/4885MAOA 4187/4885S1PR1 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.