Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925355 | 0.78 | LMNA (0.44) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL31292082 | 0.76 | NAMPT (0.39) | MEN1KMT2ACYP3A4CYP1A2ABCB11 | |
| SCHEMBL27482018 | 0.75 | CYP19A1 (0.34) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL17420592 | 0.74 | MAPK1 (0.40) | ALDH1A1LMNAPOLBKMT2AL3MBTL1 | |
| SCHEMBL3913293 | 0.73 | ALDH1A1 (0.70) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL5667254 | 0.73 | ALDH1A1 (0.70) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL4200385 | 0.73 | ALDH1A1 (0.55) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL290176 | 0.72 | CHRM2 (0.70) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL13574067 | 0.72 | CHRM2 (0.70) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 | |
| SCHEMBL13574070 | 0.72 | CHRM2 (0.70) | CHRM2CHRM1KCNH2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |