Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.83 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839781 | 0.85 | NR1H4 (0.71) | F10NR1H4NPC1RAB9APPARG | |
| SCHEMBL12447826 | 0.82 | NPC1 (0.82) | F10NR1H4DEGS1NPC1RAB9A | |
| SCHEMBL2467402 | 0.82 | PLAU (0.78) | NR1H4DEGS1NPC1RAB9AMEN1 | |
| SCHEMBL20840618 | 0.80 | NR1H4 (0.59) | F10NR1H4NPC1RAB9APPARG | |
| SCHEMBL20848006 | 0.80 | NPC1 (0.78) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6592127 | 0.80 | F10 (0.56) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13252193 | 0.79 | RAB9A (0.76) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21271819 | 0.78 | F10 (0.56) | F10NR1H4NPC1RAB9APPARG | |
| SCHEMBL15599962 | 0.78 | MEN1 (0.84) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL20839737 | 0.77 | NR1H4 (0.80) | F10NR1H4NPC1RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |