Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | CCKBR | P32239 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557090 | 0.82 | SMN1; SMN2 (0.37) | ALDH1A1LMNACSF1RNPC1TP53 | |
| SCHEMBL4021989 | 0.82 | TRPM8 (0.36) | LMNA | |
| SCHEMBL1448022 | 0.80 | LMNA (0.37) | LMNAHTTNPSR1 | |
| SCHEMBL6593091 | 0.72 | MLYCD (0.33) | LMNACSF1RRAB9ANPC1GMNN | |
| SCHEMBL4027824 | 0.70 | LMNA (0.45) | ALDH1A1PKMLMNACSF1RRAB9A | |
| SCHEMBL4247716 | 0.69 | LMNA (0.41) | PKMLMNARAB9ANPC1 | |
| SCHEMBL1447777 | 0.69 | MLYCD (0.40) | ALDH1A1LMNAHTTNPSR1 | |
| SCHEMBL4025825 | 0.68 | — | — | |
| SCHEMBL6596993 | 0.68 | NPC1 (0.35) | LMNARAB9ANPC1GMNNTP53 | |
| SCHEMBL1447382 | 0.68 | LMNA (0.54) | ALDH1A1PKMLMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351958-B1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2004-06-16 | — | — | EP | disclosed |