Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25C | P30307 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6080156 | 0.99 | KDM4E (0.35) | KDM4ETDP1FDPSPARP1ELANE | |
| SCHEMBL6601268 | 0.84 | GPR35 (0.36) | KDM4ETDP1ALOX15GPR35TSHR | |
| SCHEMBL6591659 | 0.79 | NPC1 (0.44) | KDM4ETDP1FDPSALOX15CDC25B | |
| SCHEMBL6595255 | 0.78 | FDPS (0.36) | KDM4ETDP1FDPSPARP1ELANE | |
| Hydrochloric Acid SCHEMBL6080146 | 0.77 | FDPS (0.35) | KDM4ETDP1FDPSPARP1ELANE | |
| SCHEMBL6599957 | 0.76 | CTSL (0.46) | KDM4ETDP1FDPSPARP1MAPT | |
| SCHEMBL6079951 | 0.76 | PARP1 (0.35) | KDM4ETDP1PARP1ELANE | |
| SCHEMBL6080191 | 0.74 | KDM4E (0.45) | KDM4ETDP1FDPSPARP1ELANE | |
| SCHEMBL6080058 | 0.71 | KDM4E (0.46) | KDM4ETDP1FDPSPARP1ELANE | |
| SCHEMBL6080487 | 0.70 | ALDH1A1 (0.42) | KDM4ETDP1FDPSPARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |