Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GNG2 | P59768 | 1/20 | 0.37 |
| ▸ | GNB1 | P62873 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594072 | 0.83 | RAC1 (0.40) | NCF1OPRL1PDE3BPDE3AALDH1A1 | |
| SCHEMBL6597924 | 0.76 | PDE3B (0.39) | NCF1PDE3BPDE3AALDH1A1CASP1 | |
| SCHEMBL6595121 | 0.69 | RAC1 (0.40) | NCF1OPRL1PDE3BPDE3AALDH1A1 | |
| SCHEMBL4076953 | 0.68 | ALDH1A1 (0.44) | NCF1OPRL1ALDH1A1CASP1CASP7 | |
| SCHEMBL6592403 | 0.67 | NCF1 (0.41) | NCF1OPRL1ALDH1A1CASP1CASP7 | |
| SCHEMBL2777690 | 0.64 | GNG2 (0.56) | NCF1OPRL1ALDH1A1CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL11307337 | 0.63 | GNG2 (0.55) | NCF1OPRL1ALDH1A1CASP1CASP7 | |
| SCHEMBL1120035 | 0.61 | NCF1 (1.00) | NCF1ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL29557788 | 0.61 | NCF1 (1.00) | NCF1ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL28294625 | 0.61 | NR4A2 (0.52) | NCF1OPRL1ALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | claimed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | claimed |
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |