Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.50 |
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094669 | 0.89 | CTSS (0.50) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL6598112 | 0.85 | PPARG (0.52) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL6597651 | 0.84 | BCL2 (0.59) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL19575827 | 0.83 | REN (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL4710782 | 0.83 | REN (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL4710784 | 0.83 | REN (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL2730038 | 0.80 | ACE (0.62) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL376103 | 0.80 | ACE (0.62) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL6675710 | 0.80 | CTSS (0.53) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL10143850 | 0.80 | CTSS (0.53) | CTSSCTSKCTSLCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081132-B1 | HYDROXAMIC ACID DERIVATIVES AND MEDICINAL UTILIZATION THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6610729-B1 | Inhibotors of TNF, antiinflammatory | MITSUBISHI PHARMA CORPORATION (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1081132-A1 | HYDROXAMIC ACID DERIVATIVES AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-03-07 | — | — | EP | disclosed |