Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 7/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | SOD1 | P00441 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598440 | 0.88 | HTR1A (0.74) | HTR7HTR1AHTR1DALDH1A1CYP1A2 | |
| SCHEMBL6597220 | 0.86 | HTR7 (0.59) | HTR7HTR1AHTR1DALDH1A1CYP1A2 | |
| SCHEMBL7988547 | 0.81 | HTR1A (0.81) | HTR7HTR1AHTR1DALDH1A1MAPT | |
| SCHEMBL6596051 | 0.80 | HTR1A (0.66) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7983291 | 0.80 | HTR1A (0.80) | HTR7HTR1AHTR1DALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6606640 | 0.79 | HTR1A (0.67) | HTR7HTR1AHTR1DALDH1A1CYP1A2 | |
| SCHEMBL6598632 | 0.79 | HTR1A (0.59) | HTR7HTR1AHTR1DALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6597597 | 0.78 | HTR1A (0.68) | HTR7HTR1AHTR1DALDH1A1CYP1A2 | |
| SCHEMBL7988761 | 0.77 | HTR1A (0.74) | HTR7HTR1AHTR1DALDH1A1MAPT | |
| SCHEMBL7136001 | 0.75 | ALDH1A1 (0.61) | HTR7HTR1AALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337528-B1 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | VITA LAB (ES) | 2004-08-04 | — | — | EP | disclosed |
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | LABORATORIOS VITA, S.A. (ES) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | TPH1, HTR1A, HTR5A | HTR7 15/4885HTR1A 2/4885HTR1D 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.