Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | WDR5 | P61964 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593532 | 0.83 | SIRT2 (0.40) | ALDH1A1WDR5SIRT2SMN1; SMN2LMNA | |
| SCHEMBL13234005 | 0.82 | BMPR1B (0.45) | ALDH1A1SIRT2SMN1; SMN2LMNAHTT | |
| SCHEMBL6594993 | 0.78 | LMNA (0.48) | ALDH1A1WDR5SIRT2SMN1; SMN2LMNA | |
| SCHEMBL6593277 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SIRT2SMN1; SMN2LMNAKMT2A | |
| SCHEMBL16391111 | 0.75 | MAPT (0.55) | ALDH1A1WDR5KDM4ESIRT2SMN1; SMN2 | |
| SCHEMBL30672818 | 0.75 | MAPT (0.55) | ALDH1A1WDR5KDM4ESIRT2SMN1; SMN2 | |
| SCHEMBL30672820 | 0.74 | GAA (0.48) | ALDH1A1SIRT2SMN1; SMN2SNCALMNA | |
| SCHEMBL16370713 | 0.74 | GAA (0.48) | ALDH1A1SIRT2SMN1; SMN2SNCALMNA | |
| SCHEMBL18421420 | 0.73 | GRIN1 (0.51) | ALDH1A1SIRT2SMN1; SMN2LMNAHTT | |
| SCHEMBL16370521 | 0.73 | DPP7 (0.45) | ALDH1A1SMN1; SMN2LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268475-B1 | NOVEL BENZOSULTAM OXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-1268475-A1 | NOVEL BENZOSULTAM OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6365612-B2 | Benzosultam oxazolidinone antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2002-04-02 | — | — | US | disclosed |
| US-20010047018-A1 | Novel benzosultam oxazolidinone antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2001-11-29 | — | — | US | disclosed |
| WO-2001074812-A1 | NOVEL BENZOSULTAM OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047018-A1 | Novel benzosultam oxazolidinone antibacterial agents | OXA1L, TUFM, MRPL21 | ALDH1A1 459/4885WDR5 304/4885KDM4E 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.