Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13234005 | 0.83 | BMPR1B (0.45) | SIRT2ALDH1A1ADRA2ALMNAKMT2A | |
| SCHEMBL6597900 | 0.83 | ALDH1A1 (0.40) | SIRT2ALDH1A1LMNAKMT2AWDR5 | |
| SCHEMBL6595513 | 0.80 | ATAD2 (0.37) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL6593277 | 0.80 | ALDH1A1 (0.44) | SIRT2ALDH1A1ADRA2ALMNAKMT2A | |
| SCHEMBL6594993 | 0.78 | LMNA (0.48) | SIRT2ALDH1A1ADRA2ALMNAKMT2A | |
| SCHEMBL5998932 | 0.72 | KMT2A (0.51) | SIRT2ALDH1A1ADRA2ALMNAKMT2A | |
| SCHEMBL2061323 | 0.69 | GRIN2B (0.48) | ADRA2APNMT | |
| SCHEMBL5355755 | 0.69 | GRIA2 (0.65) | ALDH1A1KMT2AMEN1RAB9AGAA | |
| SCHEMBL5505203 | 0.68 | GRIN1 (0.50) | KMT2AMEN1GAACASP1CASP3 | |
| SCHEMBL3885369 | 0.67 | SIRT2 (0.55) | SIRT2ALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268475-B1 | NOVEL BENZOSULTAM OXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 2004-09-22 | — | — | EP | disclosed |
| US-6365612-B2 | Benzosultam oxazolidinone antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2002-04-02 | — | — | US | disclosed |
| US-20010047018-A1 | Novel benzosultam oxazolidinone antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2001-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047018-A1 | Novel benzosultam oxazolidinone antibacterial agents | OXA1L, TUFM, MRPL21 | SIRT2 841/4885ALDH1A1 459/4885ADRA2A 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.