Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1194181 | 0.99 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1THRBKMT2AHPGD | |
| Bromide SCHEMBL6599927 | 0.87 | LMNA (0.34) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL3686641 | 0.84 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2AHPGDMEN1 | |
| SCHEMBL6596187 | 0.80 | KMT2A (0.35) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL1193915 | 0.79 | KMT2A (0.35) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL6621921 | 0.77 | CPT2 (0.33) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL6598655 | 0.77 | MEN1 (0.38) | ALDH1A1KMT2AHPGDMEN1POLB | |
| Hydrochloric Acid SCHEMBL5358894 | 0.76 | MEN1 (0.38) | ALDH1A1KMT2AHPGDMEN1POLB | |
| SCHEMBL6595709 | 0.75 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2AHPGDMEN1 | |
| SCHEMBL6596042 | 0.74 | KMT2A (0.48) | ALDH1A1L3MBTL1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |