Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.47 |
| ▸ | CCR9 | P51686 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602150 | 0.92 | CCR2 (0.48) | CCR2ALDH1A1POLBHSD17B10PLA2G10 | |
| SCHEMBL6598791 | 0.91 | KMT2A (0.49) | ALDH1A1POLBHSD17B10NOD2NOD1 | |
| SCHEMBL6601364 | 0.83 | PGR (0.37) | CCR9ALDH1A1POLBHSD17B10 | |
| SCHEMBL8659965 | 0.81 | MEN1 (0.40) | ALDH1A1POLBHSD17B10 | |
| SCHEMBL6601208 | 0.79 | CCR2 (0.35) | CCR2ALDH1A1POLBHSD17B10 | |
| SCHEMBL6598958 | 0.79 | ALDH1A1 (0.37) | ALDH1A1POLBHSD17B10 | |
| SCHEMBL6598493 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBHSD17B10 | |
| SCHEMBL6601171 | 0.78 | MAPT (0.43) | ALDH1A1POLBHSD17B10NOD2NOD1 | |
| SCHEMBL6599144 | 0.77 | CPT1A (0.39) | ALDH1A1POLBHSD17B10 | |
| SCHEMBL8316064 | 0.76 | FFAR1 (0.42) | ALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |