SCHEMBL659867

SCHEMBL659867

CC(C)(C)CC(C)(C)c1cccc(C(=O)O)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 3/20 0.49
HPGD P15428 2/20 0.49
ALB P02768 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ALOX15 P16050 2/20 0.45
MMP2 P08253 1/20 0.44
HMGB1 P09429 2/20 0.42
HNF4A P41235 1/20 0.42
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
SHBG P04278 1/20 0.38
LMNA P02545 1/20 0.38
CA12 O43570 3/20 0.37
CA9 Q16790 3/20 0.37
CA1 P00915 1/20 0.37
CA4 P22748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7089020 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL8672552 0.86 HNF4A (0.51) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL3831753 0.85 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDALBHSD17B10
Zinc Ion SCHEMBL7089018 0.84 KDM4E (0.37) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL1833403 0.82 CA2 (0.56) ALDH1A1HSD17B10ALOX15CYP3A4CYP2C9
SCHEMBL659868 0.81 KDM4E (0.44) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL30638079 0.80 CA2 (0.61) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL39311 0.80 CA2 (0.61) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL8878983 0.80 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL3010386 0.80 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDALBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed
CN-110741237-A Material for pressure measurement 富士胶片株式会社 2020-01-31 CN disclosed
US-8507182-B2 Method of providing lithographic printing plates EASTMAN KODAK COMPANY (US) 2013-08-13 US disclosed
US-8420297-B2 Developers and method of coloring lithographic printing members EASTMAN KODAK COMPANY (US) 2013-04-16 US disclosed
US-8247163-B2 Preparing lithographic printing plates with enhanced contrast EASTMAN KODAK COMPANY (US) 2012-08-21 US disclosed
US-8240943-B2 On-press developable imageable elements EASTMAN KODAK COMPANY (US) 2012-08-14 US disclosed
EP-2297611-B1 ON-PRESS DEVELOPABLE IMAGEABLE ELEMENTS EASTMAN KODAK CO (US) 2012-07-11 EP disclosed
EP-2440978-A1 PREPARING LITHOGRAPHC PRINTING PLATES WITH ENHANCED CONTRAST Eastman Kodak Company (US) 2012-04-18 EP disclosed
EP-2288507-B1 SUBSTRATE AND IMAGEABLE ELEMENT WITH HYDROPHILIC INTERLAYER EASTMAN KODAK CO (US) 2012-02-29 EP disclosed
US-20120045720-A1 DEVELOPERS AND METHOD OF COLORING LITHOGRAPHIC PRINTING MEMBERS KODAK REALTY INC. 2012-02-23 US disclosed
US-4682194-A MICROCAPSULES CONTAINING LEUCO DYE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
EP-0109838-B1 LIGHT AND HEAT-SENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-04-08 EP disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed
US-4598035-A LEUCO AND DISAZO DYES FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US disclosed
US-4533929-A ANIONIC SURFACTANTS AS ANTIFOGGING AGENTS; DIETHYLHEXYL SULFOSUCCINATE FUJI PHOTO FILM CO., LTD. (JP) 1985-08-06 US disclosed
US-4529681-A Microcapsules containing vinyl compound, photoinitiator and color forming compound FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 US disclosed
US-4479138-A PHENYL BENZOIC ESTER TO INCREASE SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 US disclosed
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 EP disclosed
US-4418942-A WRINKLE RESISTANCE; HYDROPHOBIC SURFACTANTS; LOW GAS PERMEABILITY FUJI PHOTO FILM CO., LTD. (JP) 1983-12-06 US disclosed
US-4273873-A BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME UNITIKA LTD. (JP) 1981-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045720-A1 DEVELOPERS AND METHOD OF COLORING LITHOGRAPHIC PRINTING MEMBERS ALG3, COG7, ALG1 ALDH1A1 1241/4885KDM4E 3679/4885HPGD 526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.