Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | LIPC | P11150 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335107 | 0.76 | TP53 (0.67) | CA12CA1CA2CA9TP53 | |
| SCHEMBL20335110 | 0.76 | TP53 (0.67) | CA12CA1CA2CA9TP53 | |
| SCHEMBL26606001 | 0.76 | CA12 (0.61) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL26606003 | 0.76 | CA12 (0.61) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL7657538 | 0.75 | MGLL (0.59) | MGLLFAAHBCHELIPCACHE | |
| Trifluoroacetic Acid SCHEMBL6602639 | 0.71 | MGLL (0.52) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL20335068 | 0.71 | CA12 (0.71) | CA12CA1CA2CA9TP53 | |
| SCHEMBL20335066 | 0.71 | CA12 (0.71) | CA12CA1CA2CA9TP53 | |
| SCHEMBL4900935 | 0.70 | ALDH1A1 (0.61) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL12149993 | 0.70 | POLB (0.63) | TP53ALDH1A1ELANEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |