Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.59 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.57 |
| ▸ | LIPC | P11150 | 2/20 | 0.51 |
| ▸ | LIPE | Q05469 | 2/20 | 0.51 |
| ▸ | LPL | P06858 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046524 | 0.82 | MGLL (0.53) | MGLLABHD16ALIPCLIPELPL | |
| SCHEMBL7043150 | 0.79 | MGLL (0.63) | MGLLABHD16ALIPCLIPEFAAH | |
| SCHEMBL7047523 | 0.77 | MGLL (0.67) | MGLLABHD16ALIPCLIPEFAAH | |
| SCHEMBL6601500 | 0.77 | ALDH1A1 (0.51) | MGLLABHD16ALIPCLIPELPL | |
| SCHEMBL6601880 | 0.76 | ALDH1A1 (0.54) | MGLLABHD16AFAAHGAAALDH1A1 | |
| SCHEMBL6552790 | 0.76 | MGLL (0.74) | MGLLABHD16ALIPCLIPEFAAH | |
| SCHEMBL11620781 | 0.75 | FAAH (0.78) | MGLLABHD16ALIPCLIPELPL | |
| Trifluoroacetic Acid SCHEMBL6601176 | 0.75 | MGLL (0.50) | MGLLABHD16ALIPCLIPELPL | |
| Trifluoroacetic Acid SCHEMBL6601602 | 0.75 | MGLL (0.50) | MGLLABHD16ALIPCLIPELPL | |
| Trifluoroacetic Acid SCHEMBL6606875 | 0.75 | MGLL (0.50) | MGLLABHD16ALIPCLIPELPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369088-B2 | ANTIDIABETIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |