Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | YAP1 | P46937 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599351 | 0.85 | CTSS (0.56) | CTSBPTPN1CTSSCTSK | |
| SCHEMBL6600308 | 0.81 | CTSS (0.52) | CTSBPTPN1PTPN2PTPN6CDC25B | |
| SCHEMBL27552033 | 0.81 | CTSS (0.52) | CTSBPTPN1PTPN2PTPN6CDC25B | |
| SCHEMBL6162914 | 0.80 | MAPK1 (0.62) | CAPN1YAP1CTSBPTPN1MAPK1 | |
| SCHEMBL6162909 | 0.80 | MAPK1 (0.62) | CAPN1YAP1CTSBPTPN1MAPK1 | |
| SCHEMBL6600504 | 0.78 | YAP1 (0.49) | CAPN1YAP1CTSBMAPK1KMT2A | |
| SCHEMBL6600505 | 0.78 | YAP1 (0.49) | CAPN1YAP1CTSBMAPK1KMT2A | |
| SCHEMBL6600519 | 0.77 | YAP1 (0.46) | CAPN1YAP1CTSBMAPK1KMT2A | |
| SCHEMBL6600260 | 0.76 | CTSC (0.45) | CTSBPTPN1PTPN2PTPN6CDC25B | |
| SCHEMBL27494688 | 0.76 | CTSC (0.45) | CTSBPTPN1PTPN2PTPN6CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |