Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.56 |
| ▸ | CTSK | P43235 | 5/20 | 0.56 |
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | PTPRB | P23467 | 9/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552033 | 0.94 | CTSS (0.52) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6600308 | 0.94 | CTSS (0.52) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL27478624 | 0.87 | CTSS (0.53) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6600491 | 0.87 | CTSS (0.53) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL7658568 | 0.85 | CTSB (0.52) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL27519418 | 0.85 | CTSB (0.52) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6599339 | 0.85 | CAPN1 (0.44) | CTSSCTSKCTSBPTPN1 | |
| SCHEMBL27494688 | 0.83 | CTSC (0.45) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6600260 | 0.83 | CTSC (0.45) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL5556443 | 0.77 | CTSS (0.68) | CTSSCTSKCTSBPTPN1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |