Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | PTPRB | P23467 | 11/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552033 | 1.00 | CTSS (0.52) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6599351 | 0.94 | CTSS (0.56) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6600491 | 0.93 | CTSS (0.53) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL27478624 | 0.93 | CTSS (0.53) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL7658568 | 0.91 | CTSB (0.52) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL27519418 | 0.91 | CTSB (0.52) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6600260 | 0.83 | CTSC (0.45) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL27494688 | 0.83 | CTSC (0.45) | CTSSCTSKCTSBPTPRBPTPN1 | |
| SCHEMBL6599339 | 0.81 | CAPN1 (0.44) | CTSSCTSKCTSBPTPN1ALDH1A1 | |
| SCHEMBL6602216 | 0.79 | MME (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1225471-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2005-11-02 | — | — | CN | disclosed |
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| CN-1176645-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1998-03-18 | — | — | CN | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |