Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632012 | 0.70 | HTR2A (0.50) | ADRA1APDPK1SIGMAR1MAOAMAOB | |
| SCHEMBL7584497 | 0.70 | PDPK1 (0.42) | ADRA1APDPK1SIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL6597324 | 0.69 | ADRA1A (0.37) | ADRA1APDPK1SIGMAR1MAOAMAOB | |
| SCHEMBL652932 | 0.69 | ADRA1A (0.37) | ADRA1APDPK1SIGMAR1MAOAMAOB | |
| SCHEMBL6447446 | 0.68 | IDO1 (0.40) | ADRA1APDPK1SIGMAR1HTR6HTR2A | |
| SCHEMBL7584485 | 0.68 | PIN1 (0.40) | ADRA1APDPK1SIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL8849605 | 0.67 | DDB1 (0.53) | ADRA1APDPK1SIGMAR1HTR2AHTR2C | |
| SCHEMBL8735629 | 0.65 | ADRA1A (0.46) | ADRA1APDPK1SIGMAR1IDO1CYP2D6 | |
| SCHEMBL942815 | 0.65 | PDPK1 (0.43) | ADRA1APDPK1SIGMAR1MAOAMAOB | |
| SCHEMBL5709417 | 0.64 | PRCP (0.56) | SIGMAR1HTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964027-B1 | Flame-retarded transparent plastics | BROMINE COMPOUNDS LTD (IL) | 2004-05-12 | — | — | EP | disclosed |
| US-6632870-B2 | Mixture containing polyhalogenated trimethylphenyl indanecompound | BROMINE COMPOUNDS LTD. (IL) | 2003-10-14 | — | — | US | disclosed |
| US-20010021742-A1 | Flame-retarded transparent plastics | BROMINE COMPOUNDS LTD. (IL) | 2001-09-13 | — | — | US | disclosed |
| EP-0964027-A1 | Flame-retarded transparent plastics | Bromine Compounds Ltd. (IL) | 1999-12-15 | — | — | EP | disclosed |