Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593859 | 0.85 | GPR35 (0.56) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL6594662 | 0.84 | GPR35 (0.51) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL6590987 | 0.84 | GPR35 (0.51) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL6588975 | 0.84 | GPR35 (0.51) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL6597503 | 0.82 | GPR35 (0.49) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL6595262 | 0.81 | ALOX15 (0.51) | GPR35ALOX15IGFBP3KDM4EL3MBTL1 | |
| SCHEMBL6590519 | 0.80 | GPR35 (0.47) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL6591557 | 0.80 | GPR35 (0.47) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL6591560 | 0.80 | GPR35 (0.47) | GPR35ALOX15IGFBP3KDM4ETDP1 | |
| SCHEMBL975858 | 0.79 | ALOX15 (0.56) | GPR35ALOX15IGFBP3KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |