Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080867 | 0.88 | ALDH1A1 (0.43) | GPR35ALDH1A1TDP1TRIM24HPGD | |
| SCHEMBL6591557 | 0.87 | GPR35 (0.47) | GPR35ALDH1A1TDP1HPGDALOX15 | |
| SCHEMBL6591560 | 0.87 | GPR35 (0.47) | GPR35ALDH1A1TDP1HPGDALOX15 | |
| SCHEMBL6594662 | 0.83 | GPR35 (0.51) | GPR35ALDH1A1TDP1ALOX15IGFBP3 | |
| SCHEMBL6080551 | 0.83 | KDM4E (0.39) | GPR35TDP1ALOX15IGFBP3TSHR | |
| SCHEMBL6599593 | 0.82 | GPR35 (0.52) | GPR35ALDH1A1TDP1ALOX15IGFBP3 | |
| SCHEMBL6593859 | 0.82 | GPR35 (0.56) | GPR35ALDH1A1TDP1ALOX15IGFBP3 | |
| SCHEMBL6588975 | 0.81 | GPR35 (0.51) | GPR35ALDH1A1TDP1ALOX15IGFBP3 | |
| SCHEMBL6590987 | 0.81 | GPR35 (0.51) | GPR35ALDH1A1TDP1ALOX15IGFBP3 | |
| SCHEMBL6595262 | 0.77 | ALOX15 (0.51) | GPR35ALDH1A1ALOX15IGFBP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |