Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080169 | 0.87 | MAPT (0.41) | GPR35ALOX15PIM1NQO2KDM4E | |
| SCHEMBL6593859 | 0.84 | GPR35 (0.56) | GPR35ALOX15PIM1IGFBP3IGFBP5 | |
| SCHEMBL6599593 | 0.84 | GPR35 (0.52) | GPR35ALOX15PIM1IGFBP3IGFBP5 | |
| SCHEMBL6594662 | 0.83 | GPR35 (0.51) | GPR35ALOX15PIM1IGFBP3IGFBP5 | |
| SCHEMBL6588975 | 0.83 | GPR35 (0.51) | GPR35ALOX15PIM1IGFBP3IGFBP5 | |
| SCHEMBL6080581 | 0.82 | GPR35 (0.39) | GPR35ALOX15IGFBP3IGFBP5KDM4E | |
| SCHEMBL6597503 | 0.81 | GPR35 (0.49) | GPR35ALOX15PIM1IGFBP3KDM4E | |
| SCHEMBL6595262 | 0.80 | ALOX15 (0.51) | GPR35ALOX15IGFBP3KDM4EL3MBTL1 | |
| SCHEMBL9830239 | 0.79 | NQO2 (0.46) | ALOX15NQO2L3MBTL1LMNAALDH1A1 | |
| SCHEMBL6591557 | 0.79 | GPR35 (0.47) | GPR35ALOX15PIM1IGFBP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |