Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601202 | 0.85 | S1PR1 (0.39) | S1PR1PPARGPPARA | |
| SCHEMBL6599461 | 0.83 | FFAR1 (0.41) | ACHE | |
| SCHEMBL6598947 | 0.81 | ALDH1A1 (0.42) | HDAC8EPHX2NR1H4 | |
| SCHEMBL6598501 | 0.77 | PLA2G2A (0.38) | S1PR1 | |
| SCHEMBL6597512 | 0.77 | PLA2G2A (0.37) | S1PR1PPARGPPARA | |
| SCHEMBL6599513 | 0.77 | S1PR1 (0.35) | P2RX3S1PR1 | |
| SCHEMBL8664601 | 0.76 | THRA (0.42) | S1PR1 | |
| SCHEMBL5811105 | 0.76 | POLB (0.35) | HDAC8 | |
| SCHEMBL6598919 | 0.75 | S1PR1 (0.36) | S1PR1 | |
| SCHEMBL6598918 | 0.75 | S1PR1 (0.36) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |