Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044319 | 0.84 | ABHD16A (0.53) | LMNAKMT2AABHD16AALDH1A1MAPT | |
| SCHEMBL6601531 | 0.84 | ABHD16A (0.50) | MEN1KMT2AABHD16AALDH1A1MAPT | |
| SCHEMBL7045584 | 0.83 | PGR (0.58) | LMNAKMT2AMAPK1ABHD16AALDH1A1 | |
| SCHEMBL7040851 | 0.79 | FFAR1 (0.53) | LMNAABHD16AFAAHMGLL | |
| SCHEMBL7040759 | 0.77 | ABHD16A (0.58) | ABHD16AFAAHMGLL | |
| SCHEMBL7040692 | 0.76 | MGLL (0.53) | LMNAABHD16AALDH1A1MAPTHDAC4 | |
| SCHEMBL6073585 | 0.73 | ALDH1A1 (0.62) | LMNAHTTSMN1; SMN2CA12CA9 | |
| SCHEMBL7047556 | 0.72 | MGLL (0.57) | LMNAHTTMEN1KMT2AALOX15 | |
| SCHEMBL6601106 | 0.72 | TP53 (0.62) | HTTMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL94655 | 0.72 | LMNA (0.77) | LMNAHTTSMN1; SMN2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |