Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040692 | 0.81 | MGLL (0.53) | ALDH1A1TDP1HDAC1MAPT | |
| SCHEMBL22422345 | 0.77 | TP53 (1.00) | TP53HTTALDH1A1GFERMEN1 | |
| SCHEMBL7045584 | 0.75 | PGR (0.58) | ALDH1A1KMT2APKMTDP1MAPT | |
| SCHEMBL10192086 | 0.73 | MEN1 (0.75) | TP53HTTALDH1A1GFERMEN1 | |
| SCHEMBL7040759 | 0.73 | ABHD16A (0.58) | — | |
| SCHEMBL6599976 | 0.72 | LMNA (0.56) | HTTALDH1A1MEN1KMT2APKM | |
| SCHEMBL6363732 | 0.72 | GFER (0.98) | TP53HTTALDH1A1GFERMEN1 | |
| SCHEMBL17210223 | 0.72 | ALDH1A1 (1.00) | TP53HTTALDH1A1MEN1KMT2A | |
| SCHEMBL6362807 | 0.71 | GFER (1.00) | TP53HTTALDH1A1GFERMEN1 | |
| SCHEMBL7043957 | 0.71 | MGLL (0.52) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |