Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 3/20 | 0.35 |
| ▸ | CCKBR | P32239 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600367 | 0.83 | CTSS (0.56) | CTSSCTSBCTSKPTPN1GHSR | |
| SCHEMBL6600601 | 0.83 | GHSR (0.51) | CTSSCTSBCTSKGHSRMEN1 | |
| SCHEMBL6600523 | 0.78 | ALDH1A1 (0.43) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL6589174 | 0.72 | CTSS (0.64) | CTSSCTSBCTSKPTPN1GHSR | |
| SCHEMBL5552762 | 0.72 | CTSS (0.64) | CTSSCTSBCTSKPTPN1GHSR | |
| SCHEMBL6600519 | 0.71 | YAP1 (0.46) | CTSSCTSBCTSKGHSRMEN1 | |
| SCHEMBL1519731 | 0.71 | CTSS (0.74) | CTSSCTSBCTSKPTPN1ACE | |
| SCHEMBL3821361 | 0.71 | CTSS (0.74) | CTSSCTSBCTSKPTPN1ACE | |
| SCHEMBL29436862 | 0.71 | CTSS (0.74) | CTSSCTSBCTSKPTPN1ACE | |
| SCHEMBL29397962 | 0.71 | CTSS (0.74) | CTSSCTSBCTSKPTPN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |