Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTPRB | P23467 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933288 | 0.88 | MAPK1 (0.43) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6600519 | 0.75 | YAP1 (0.46) | ALDH1A1MEN1KMT2APOLBSTS | |
| SCHEMBL2340961 | 0.69 | PTPRB (0.52) | MEN1KMT2AUSP30KDM4EPTPRB | |
| SCHEMBL7658402 | 0.68 | PTPRB (0.40) | MEN1KMT2AUSP30PTPRBSTS | |
| SCHEMBL5762606 | 0.65 | THRB (0.54) | MEN1KMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL5889409 | 0.64 | STS (0.60) | MEN1KMT2ASMN1; SMN2USP30GAA | |
| SCHEMBL6600367 | 0.64 | CTSS (0.56) | ALDH1A1PTPRB | |
| SCHEMBL6374590 | 0.64 | NPSR1 (0.47) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL23539486 | 0.63 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL6162914 | 0.63 | MAPK1 (0.62) | MEN1KMT2ASTSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |