Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660881 | 0.89 | DHFR (0.38) | DHFRAPLNRMAPT | |
| SCHEMBL667145 | 0.88 | DHFR (0.37) | DHFRAPLNR | |
| SCHEMBL663011 | 0.88 | APLNR (0.40) | DHFRAPLNR | |
| SCHEMBL661889 | 0.85 | ALKBH1 (0.37) | DHFRAPLNRMAPT | |
| SCHEMBL667685 | 0.84 | CCR2 (0.31) | — | |
| SCHEMBL658703 | 0.84 | PPARG (0.41) | — | |
| SCHEMBL667684 | 0.83 | PPARG (0.37) | — | |
| SCHEMBL504786 | 0.77 | ACHE (0.38) | APLNR | |
| SCHEMBL660776 | 0.77 | CACNA2D1 (0.40) | DHFRAPLNRMAPT | |
| SCHEMBL9948598 | 0.76 | ACHE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046308-A1 | NOVEL ALPHA-PHENOXYBENZENEACETIC ACID DERIVATIVE AND PHARMACEUTICAL PREPARATION COMPRISING SAME | KOWA COMPANY, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046308-A1 | NOVEL ALPHA-PHENOXYBENZENEACETIC ACID DERIVATIVE AND PHARMACEUTICAL PREPARATION COMPRISING SAME | PPARA, PPARG, PPARD | DHFR 2581/4885APLNR 710/4885MAPT 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.