Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599863 | 0.89 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL6602374 | 0.86 | MMP9 (0.41) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL6600776 | 0.84 | GHSR (0.42) | GHSRTACR1 | |
| SCHEMBL6600092 | 0.83 | GHSR (0.39) | GHSR | |
| SCHEMBL6600882 | 0.81 | MMP9 (0.42) | TACR1 | |
| SCHEMBL6317958 | 0.77 | MC4R (0.43) | HTR2AHTR2CHTR2BTACR1 | |
| SCHEMBL6613846 | 0.77 | MC4R (0.43) | HTR2AHTR2CHTR2BTACR1 | |
| SCHEMBL6600960 | 0.76 | USP30 (0.41) | TACR1 | |
| SCHEMBL6602359 | 0.76 | TACR1 (0.41) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL6602292 | 0.76 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |