Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 14/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602359 | 0.90 | TACR1 (0.41) | MMP9MMP8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6600882 | 0.90 | MMP9 (0.42) | MMP9MMP8TACR1 | |
| SCHEMBL6600571 | 0.86 | ITGB3 (0.39) | SLC6A2SLC6A4SLC6A3TACR1HTR2A | |
| SCHEMBL6320628 | 0.84 | CTSS (0.52) | MMP9MMP8TACR1CTSLCTSB | |
| SCHEMBL6601069 | 0.83 | SRC (0.46) | MMP9MMP8CTSLCTSBCTSS | |
| SCHEMBL7061546 | 0.82 | MMP9 (0.40) | MMP9MMP8TACR1 | |
| SCHEMBL6599863 | 0.81 | SLC6A2 (0.40) | MMP9MMP8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6614582 | 0.81 | MMP9 (0.45) | MMP9MMP8TACR1 | |
| SCHEMBL6600500 | 0.81 | MMP9 (0.45) | MMP9MMP8TACR1 | |
| SCHEMBL2576148 | 0.80 | TACR1 (0.40) | MMP9MMP8TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |