Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600571 | 0.89 | ITGB3 (0.39) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL6600882 | 0.85 | MMP9 (0.42) | TACR1MMP9MMP8 | |
| SCHEMBL6600776 | 0.85 | GHSR (0.42) | TACR1GHSRMMP9MMP8 | |
| SCHEMBL6600960 | 0.85 | USP30 (0.41) | TACR1 | |
| SCHEMBL6602374 | 0.81 | MMP9 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL6600092 | 0.80 | GHSR (0.39) | GHSRMMP9MMP8 | |
| SCHEMBL6613846 | 0.79 | MC4R (0.43) | TACR1HTR2AHTR2CHTR2BMMP9 | |
| SCHEMBL6317958 | 0.79 | MC4R (0.43) | TACR1HTR2AHTR2CHTR2BMMP9 | |
| SCHEMBL7061546 | 0.78 | MMP9 (0.40) | TACR1MMP9MMP8 | |
| SCHEMBL6600500 | 0.77 | MMP9 (0.45) | TACR1GHSRMMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | claimed |
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |