Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 14/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061546 | 0.91 | MMP9 (0.40) | MMP9MMP8TACR1 | |
| SCHEMBL6601809 | 0.90 | TACR1 (0.43) | MMP9MMP8TACR1 | |
| SCHEMBL27477312 | 0.90 | TACR1 (0.43) | MMP9MMP8TACR1 | |
| SCHEMBL6602374 | 0.90 | MMP9 (0.41) | MMP9MMP8TACR1 | |
| SCHEMBL2576148 | 0.89 | TACR1 (0.40) | MMP9MMP8TACR1MC4RMC3R | |
| SCHEMBL6601864 | 0.88 | TACR1 (0.39) | MMP9MMP8TACR1MC4RMC3R | |
| SCHEMBL6601553 | 0.87 | MMP9 (0.40) | MMP9MMP8TACR1MC4RMC3R | |
| SCHEMBL6601229 | 0.86 | KMT2A (0.45) | TACR1CAPN1ALDH1A1 | |
| SCHEMBL6599863 | 0.85 | SLC6A2 (0.40) | MMP9MMP8TACR1 | |
| SCHEMBL6600500 | 0.83 | MMP9 (0.45) | MMP9MMP8TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |