Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660037 | 0.87 | NPC1 (0.36) | HTTNPSR1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5363423 | 0.71 | ALDH1A1 (0.36) | HTTNPSR1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL298106 | 0.68 | RAB9A (0.31) | HTTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL298638 | 0.67 | LMNA (0.32) | RECQLALDH1A1 | |
| SCHEMBL298688 | 0.66 | ALDH1A1 (0.38) | NPSR1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL660291 | 0.65 | KMT2A (0.38) | HTTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7798097 | 0.63 | KMT2A (0.36) | HTTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7066427 | 0.61 | HRH2 (0.34) | HTTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27871675 | 0.60 | KMT2A (0.33) | MEN1KMT2A | |
| SCHEMBL659354 | 0.60 | ALDH1A1 (0.33) | HTTNPSR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | claimed |
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | HTT 75/4885NPSR1 3243/4885GRM5 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.