Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606642 | 0.92 | DPP8 (0.45) | DPP8DPP4DPP7FKBP1APRCP | |
| SCHEMBL6603737 | 0.90 | DPP4 (0.47) | DPP8DPP4DPP7FKBP1APRCP | |
| SCHEMBL7454452 | 0.81 | DPP8 (0.44) | DPP8DPP4DPP7FKBP1AALDH1A1 | |
| SCHEMBL6605416 | 0.79 | FKBP1A (0.49) | DPP8DPP4DPP7FKBP1AALDH1A1 | |
| SCHEMBL29454953 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9513187 | 0.72 | PRCP (0.54) | FKBP1APRCPACE | |
| Trifluoroacetic Acid SCHEMBL6600269 | 0.72 | FKBP1A (0.44) | DPP8DPP4DPP7FKBP1AACE | |
| SCHEMBL7458698 | 0.70 | MCHR1 (0.53) | ALDH1A1 | |
| SCHEMBL562368 | 0.70 | LMNA (0.56) | ALDH1A1L3MBTL1 | |
| SCHEMBL29004401 | 0.70 | LMNA (0.56) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924210-B1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | WYETH K K (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0632039-B1 | 2-[1-(1,3-Thiazolin-2-yl)azetidin-3-yl]thio-carbapenem derivatives | WYETH LEDERLE JAPAN LTD (JP) | 2002-01-30 | — | — | EP | disclosed |
| EP-0924210-A1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5534510-A | ORALLY ADMINISTRABLE THIENAMYCIN ANTIBIOTICS; BETA-LACTAMASE INHIBITORS | LEDERLE (JAPAN), LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0632039-A1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |