Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601649 | 0.90 | DPP8 (0.45) | DPP4DPP8DPP7FKBP1APRCP | |
| SCHEMBL6606642 | 0.90 | DPP8 (0.45) | DPP4DPP8DPP7FKBP1APRCP | |
| SCHEMBL7454452 | 0.84 | DPP8 (0.44) | DPP4DPP8DPP7FKBP1AACE | |
| SCHEMBL6605416 | 0.82 | FKBP1A (0.49) | DPP4DPP8DPP7FKBP1APREP | |
| Trifluoroacetic Acid SCHEMBL6600269 | 0.77 | FKBP1A (0.44) | DPP4DPP8DPP7FKBP1AACE | |
| SCHEMBL30610198 | 0.76 | ALDH1A1 (0.50) | DPP4DPP8DPP7 | |
| SCHEMBL2082597 | 0.74 | PREP (0.69) | FKBP1AACEPREP | |
| SCHEMBL562368 | 0.74 | LMNA (0.56) | PREP | |
| SCHEMBL29004401 | 0.74 | LMNA (0.56) | PREP | |
| SCHEMBL6216080 | 0.74 | PREP (0.54) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924210-B1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | WYETH K K (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0632039-B1 | 2-[1-(1,3-Thiazolin-2-yl)azetidin-3-yl]thio-carbapenem derivatives | WYETH LEDERLE JAPAN LTD (JP) | 2002-01-30 | — | — | EP | disclosed |
| EP-0924210-A1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5534510-A | ORALLY ADMINISTRABLE THIENAMYCIN ANTIBIOTICS; BETA-LACTAMASE INHIBITORS | LEDERLE (JAPAN), LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0632039-A1 | 2-(1-(1,3-Thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |